Alprazolam
Brand names: Xanax|Last verified: 2026-09-12
FAA Pathway: Do Not Fly (anti-anxiety) — routine use requires deferral; chronic use is Do Not Issue
The FAA's Do Not Fly table lists alprazolam (Xanax) among anti-anxiety medications that can impair performance even when you feel alert. If you use it routinely, the AME must defer, and an ongoing prescription for chronic use of a controlled substance is on the Do Not Issue list. Do not fly while taking it or until at least 5 times its maximum half-life has passed since your last dose. The underlying anxiety condition is evaluated separately.
Related Resources
Pilot Tip
Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.
Certification Details
Sources
- FAA Do Not Issue Table
- FAA Do-Not-Issue/Do-Not-Fly Table (faa.gov/ame_guide/media/DNI_DNF_tables.pdf)
Last verified: 2026-09-12
Frequently Asked Questions
Is Alprazolam allowed for pilots?
The FAA considers Alprazolam (Xanax) to be "Disqualifying" for medical certification purposes. The FAA's Do Not Fly table lists alprazolam (Xanax) among anti-anxiety medications that can impair performance even when you feel alert. If you use it routinely, the AME must defer, and an ongoing prescription for chronic use of a controlled substance is on the Do Not Issue list. Do not fly while taking it or until at least 5 times its maximum half-life has passed since your last dose. The underlying anxiety condition is evaluated separately.
What is the FAA status of Alprazolam?
Alprazolam has a status of "Disqualifying" under FAA medical certification policy. The certification pathway is: Do Not Fly (anti-anxiety) — routine use requires deferral; chronic use is Do Not Issue.
Can I fly while taking Alprazolam?
Alprazolam is currently disqualifying for FAA medical certification. You cannot fly while taking this medication. A washout period and evaluation are typically required after discontinuation. Consult an AME or aviation attorney before making any medication changes.
Important Notice
The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.
The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.