Penicillin AntibioticGenerally Approved

Amoxicillin

Brand names: Amoxil, Trimox|Last verified: 2026-03-01

FAA Pathway: Generally acceptable — underlying infection must not impair flight

Amoxicillin is generally acceptable for pilots. The key consideration is the underlying infection being treated — pilots should not fly while acutely ill. Once feeling well and infection is resolving, flying is typically permissible.

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Pilot Tip

Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.

Certification Details

Key Requirements
Underlying infection must not impair flight safety
Wait Period
No specific wait for the medication itself
Certificate Classes
All classes eligible
Notes
Do not fly while acutely ill regardless of antibiotic use

Sources

  • FAA AME Guide, Pharmaceuticals

Last verified: 2026-03-01

Frequently Asked Questions

Is Amoxicillin allowed for pilots?

The FAA considers Amoxicillin (Amoxil, Trimox) to be "Generally Approved" for medical certification purposes. Amoxicillin is generally acceptable for pilots. The key consideration is the underlying infection being treated — pilots should not fly while acutely ill. Once feeling well and infection is resolving, flying is typically permissible.

What is the FAA status of Amoxicillin?

Amoxicillin has a status of "Generally Approved" under FAA medical certification policy. The certification pathway is: Generally acceptable — underlying infection must not impair flight.

Can I fly while taking Amoxicillin?

Amoxicillin is generally compatible with flying. However, you must report it on your FAA medical application (Form 8500-8) and ensure you are not experiencing side effects that could impair flight safety. Always consult your Aviation Medical Examiner (AME).

Important Notice

The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.

The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.