Muscle Relaxant (Centrally-Acting)Disqualifying

Baclofen

Brand names: Lioresal, Gablofen|Last verified: 2026-03-01

FAA Pathway: Do Not Issue (DNI) list

Baclofen is on the FAA's DNI list. It is a centrally-acting muscle relaxant with sedating effects that are disqualifying for aviation. The underlying spasticity condition may also affect certification.

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Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.

Certification Details

FAA Status
Do Not Issue (DNI) list
Sedation
Significant CNS effects including drowsiness and confusion
Certificate Classes
All classes affected
Notes
Abrupt discontinuation can cause seizures — taper under medical supervision

Sources

  • FAA Do Not Issue Table

Last verified: 2026-03-01

Frequently Asked Questions

Is Baclofen allowed for pilots?

The FAA considers Baclofen (Lioresal, Gablofen) to be "Disqualifying" for medical certification purposes. Baclofen is on the FAA's DNI list. It is a centrally-acting muscle relaxant with sedating effects that are disqualifying for aviation. The underlying spasticity condition may also affect certification.

What is the FAA status of Baclofen?

Baclofen has a status of "Disqualifying" under FAA medical certification policy. The certification pathway is: Do Not Issue (DNI) list.

Can I fly while taking Baclofen?

Baclofen is currently disqualifying for FAA medical certification. You cannot fly while taking this medication. A washout period and evaluation are typically required after discontinuation. Consult an AME or aviation attorney before making any medication changes.

Important Notice

The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.

The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.