Alpha-2 Agonist Eye Drops (Glaucoma)Generally Approved

Brimonidine (Ophthalmic)

Brand names: Alphagan, Alphagan P|Last verified: 2026-03-01

FAA Pathway: Standard issuance by AME; glaucoma evaluation required

Brimonidine eye drops for glaucoma are generally compatible with FAA certification. Topical use has minimal systemic absorption. The underlying glaucoma diagnosis requires visual field evaluation to meet FAA standards.

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Related Resources

Pilot Tip

Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.

Certification Details

Key Requirements

Visual field testing must meet FAA standards

Certificate Classes

All classes eligible if visual fields adequate

Side Effects to Report

Ocular allergic reactions, fatigue (rare systemic)

Notes

Topical medication — minimal systemic effects expected

Sources

FAA AME Guide, Ophthalmology

Last verified: 2026-03-01

Frequently Asked Questions

Is Brimonidine (Ophthalmic) allowed for pilots?

The FAA considers Brimonidine (Ophthalmic) (Alphagan, Alphagan P) to be "Generally Approved" for medical certification purposes. Brimonidine eye drops for glaucoma are generally compatible with FAA certification. Topical use has minimal systemic absorption. The underlying glaucoma diagnosis requires visual field evaluation to meet FAA standards.

What is the FAA status of Brimonidine (Ophthalmic)?

Brimonidine (Ophthalmic) has a status of "Generally Approved" under FAA medical certification policy. The certification pathway is: Standard issuance by AME; glaucoma evaluation required.

Can I fly while taking Brimonidine (Ophthalmic)?

Brimonidine (Ophthalmic) is generally compatible with flying. However, you must report it on your FAA medical application (Form 8500-8) and ensure you are not experiencing side effects that could impair flight safety. Always consult your Aviation Medical Examiner (AME).

Important Notice

The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.

The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.