Barbiturate Combination (Headache)Disqualifying

Butalbital Combinations

Brand names: Fioricet, Fiorinal|Last verified: 2026-09-12

FAA Pathway: Unacceptable — prohibited migraine relief medication

The FAA's migraine medication guidance lists butalbital combinations — acetaminophen with butalbital (Fioricet) and aspirin with butalbital (Fiorinal) — as unacceptable, alone or in any combination product. An AME cannot issue while you are using them. Other migraine relief options, such as triptans and gepants, are acceptable for occasional use with specific no-fly times.

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Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.

Certification Details

FAA Status
Unacceptable (FAA Migraine Medication guidance, updated 08/26/2026)
Also Unacceptable
All opioid analgesics and Midrin (acetaminophen + isometheptene + dichloralphenazone) for migraine
Acceptable Alternatives
Triptans (24–48 hours), gepants such as Nurtec or Ubrelvy (24 hours) — occasional use only
Certificate Classes
All classes — the AME must defer

Sources

  • FAA AME Guide — Pharmaceuticals: Migraine (faa.gov/ame_guide/media/Migraine_Medication.pdf)

Last verified: 2026-09-12

Frequently Asked Questions

Is Butalbital Combinations allowed for pilots?

The FAA considers Butalbital Combinations (Fioricet, Fiorinal) to be "Disqualifying" for medical certification purposes. The FAA's migraine medication guidance lists butalbital combinations — acetaminophen with butalbital (Fioricet) and aspirin with butalbital (Fiorinal) — as unacceptable, alone or in any combination product. An AME cannot issue while you are using them. Other migraine relief options, such as triptans and gepants, are acceptable for occasional use with specific no-fly times.

What is the FAA status of Butalbital Combinations?

Butalbital Combinations has a status of "Disqualifying" under FAA medical certification policy. The certification pathway is: Unacceptable — prohibited migraine relief medication.

Can I fly while taking Butalbital Combinations?

Butalbital Combinations is currently disqualifying for FAA medical certification. You cannot fly while taking this medication. A washout period and evaluation are typically required after discontinuation. Consult an AME or aviation attorney before making any medication changes.

Important Notice

The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.

The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.