Cardiac GlycosideConditionally Approved

Digoxin

Brand names: Lanoxin|Last verified: 2026-03-01

FAA Pathway: Special Issuance required — cardiac evaluation mandatory

Digoxin requires Special Issuance evaluation. Used for heart failure and atrial fibrillation, both the medication and underlying cardiac condition require thorough evaluation. Narrow therapeutic index makes monitoring critical.

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Pilot Tip

Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.

Certification Details

Key Requirements
Stable digoxin level, cardiac evaluation
Certificate Classes
Depends on underlying cardiac condition
Monitoring
Serum digoxin levels, electrolytes, renal function, ECG
Notes
Narrow therapeutic index — toxicity risk with dehydration

Sources

  • FAA AME Guide, Cardiology

Last verified: 2026-03-01

Frequently Asked Questions

Is Digoxin allowed for pilots?

The FAA considers Digoxin (Lanoxin) to be "Conditionally Approved" for medical certification purposes. Digoxin requires Special Issuance evaluation. Used for heart failure and atrial fibrillation, both the medication and underlying cardiac condition require thorough evaluation. Narrow therapeutic index makes monitoring critical.

What is the FAA status of Digoxin?

Digoxin has a status of "Conditionally Approved" under FAA medical certification policy. The certification pathway is: Special Issuance required — cardiac evaluation mandatory.

Can I fly while taking Digoxin?

Flying while taking Digoxin may be possible through the FAA's Special Issuance process. You will need to meet specific requirements and obtain approval before exercising pilot privileges. Consult an experienced AME for guidance.

Important Notice

The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.

The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.