Isotretinoin
Brand names: Accutane, Claravis, Absorica|Last verified: 2026-09-12
FAA Pathway: Not acceptable while taking — must be discontinued at least 2 weeks before FAA consideration
You cannot fly while taking oral isotretinoin. The FAA requires that it be permanently discontinued for at least 2 weeks, confirmed by the prescribing physician, before you can be considered, because it can cause decreased night vision and depression — effects that can occur even after stopping. You will also need an eye evaluation and a signed statement confirming no visual or psychiatric symptoms and acknowledging that you must get FAA clearance before flying if you resume it. Topical acne medications and oral antibiotics such as tetracycline are acceptable.
Related Resources
Pilot Tip
Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.
Certification Details
Sources
- FAA AME Guide — Pharmaceuticals: Acne (faa.gov/ame_guide/pharm/acne)
Last verified: 2026-09-12
Frequently Asked Questions
Is Isotretinoin allowed for pilots?
The FAA considers Isotretinoin (Accutane, Claravis, Absorica) to be "Conditionally Approved" for medical certification purposes. You cannot fly while taking oral isotretinoin. The FAA requires that it be permanently discontinued for at least 2 weeks, confirmed by the prescribing physician, before you can be considered, because it can cause decreased night vision and depression — effects that can occur even after stopping. You will also need an eye evaluation and a signed statement confirming no visual or psychiatric symptoms and acknowledging that you must get FAA clearance before flying if you resume it. Topical acne medications and oral antibiotics such as tetracycline are acceptable.
What is the FAA status of Isotretinoin?
Isotretinoin has a status of "Conditionally Approved" under FAA medical certification policy. The certification pathway is: Not acceptable while taking — must be discontinued at least 2 weeks before FAA consideration.
Can I fly while taking Isotretinoin?
Flying while taking Isotretinoin may be possible through the FAA's Special Issuance process. You will need to meet specific requirements and obtain approval before exercising pilot privileges. Consult an experienced AME for guidance.
Important Notice
The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.
The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.