Lamotrigine
Brand names: Lamictal|Last verified: 2026-09-12
FAA Pathway: Do Not Issue (DNI) — seizure medication / mood stabilizer
Lamotrigine is not acceptable for FAA medical certification. The FAA's Do Not Issue table covers seizure medications even when used for non-seizure conditions, and mood stabilizers are also on the list. The FAA's migraine guidance lists lamotrigine as unacceptable for migraine prevention. An AME cannot issue while you are taking it; clearance from the FAA is required.
Related Resources
Pilot Tip
Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.
Certification Details
Sources
- FAA AME Guide, Neurology / Psychiatry
- FAA Do-Not-Issue/Do-Not-Fly Table (faa.gov/ame_guide/media/DNI_DNF_tables.pdf)
- FAA AME Guide — Pharmaceuticals: Migraine (faa.gov/ame_guide/media/Migraine_Medication.pdf)
Last verified: 2026-09-12
Frequently Asked Questions
Is Lamotrigine allowed for pilots?
The FAA considers Lamotrigine (Lamictal) to be "Disqualifying" for medical certification purposes. Lamotrigine is not acceptable for FAA medical certification. The FAA's Do Not Issue table covers seizure medications even when used for non-seizure conditions, and mood stabilizers are also on the list. The FAA's migraine guidance lists lamotrigine as unacceptable for migraine prevention. An AME cannot issue while you are taking it; clearance from the FAA is required.
What is the FAA status of Lamotrigine?
Lamotrigine has a status of "Disqualifying" under FAA medical certification policy. The certification pathway is: Do Not Issue (DNI) — seizure medication / mood stabilizer.
Can I fly while taking Lamotrigine?
Lamotrigine is currently disqualifying for FAA medical certification. You cannot fly while taking this medication. A washout period and evaluation are typically required after discontinuation. Consult an AME or aviation attorney before making any medication changes.
Important Notice
The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.
The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.