CNS Stimulant (ADHD Medication)Disqualifying

Lisdexamfetamine

Brand names: Vyvanse|Last verified: 2026-09-12

FAA Pathway: Do Not Issue (DNI) — current use not acceptable; ADHD Fast Track or Standard Track evaluation after stopping

Lisdexamfetamine (Vyvanse) is an ADHD medication on the FAA's Do Not Issue list. If you currently take it, the AME must defer. After stopping, you must be off it at least 90 days before Standard Track testing by an FAA HIMS neuropsychologist. If you haven't taken any ADHD medication in 4 years and meet the other Fast Track criteria, your AME may be able to issue.

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Pilot Tip

Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.

Certification Details

FAA Status

Do Not Issue (DNI) — ADHD medications and stimulants

Current Use

Not acceptable, including PRN use; the AME must defer

Washout Period

At least 90 days off before Standard Track testing

Evaluation Path

Used in the past 4 years: Standard Track (in-person HIMS neuropsychologist testing, then FAA review). None in 4 years and no other psychiatric history: Fast Track may allow AME issuance

Drug Testing

Standard Track requires separate urine tests for amphetamines and methylphenidate within 24 hours after testing

Sources

FAA Do Not Issue Table
FAA Do-Not-Issue/Do-Not-Fly Table (faa.gov/ame_guide/media/DNI_DNF_tables.pdf)
FAA AME Guide — Pharmaceuticals: Controlled Substances and CBD (faa.gov/ame_guide/media/Controlled_Substances_and_CBD_Products.pdf)

Last verified: 2026-09-12

Frequently Asked Questions

Is Lisdexamfetamine allowed for pilots?

The FAA considers Lisdexamfetamine (Vyvanse) to be "Disqualifying" for medical certification purposes. Lisdexamfetamine (Vyvanse) is an ADHD medication on the FAA's Do Not Issue list. If you currently take it, the AME must defer. After stopping, you must be off it at least 90 days before Standard Track testing by an FAA HIMS neuropsychologist. If you haven't taken any ADHD medication in 4 years and meet the other Fast Track criteria, your AME may be able to issue.

What is the FAA status of Lisdexamfetamine?

Lisdexamfetamine has a status of "Disqualifying" under FAA medical certification policy. The certification pathway is: Do Not Issue (DNI) — current use not acceptable; ADHD Fast Track or Standard Track evaluation after stopping.

Can I fly while taking Lisdexamfetamine?

Lisdexamfetamine is currently disqualifying for FAA medical certification. You cannot fly while taking this medication. A washout period and evaluation are typically required after discontinuation. Consult an AME or aviation attorney before making any medication changes.

Important Notice

The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.

The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.