Sympathomimetic + Anticonvulsant (Weight Loss)Disqualifying

Phentermine-Topiramate

Brand names: Qsymia|Last verified: 2026-09-12

FAA Pathway: Unacceptable — prohibited weight loss medication

The FAA lists phentermine-topiramate (Qsymia) as an unacceptable weight loss medication, prohibited as a single agent or in any combination product. Sympathomimetic weight loss drugs such as phentermine are also on the FAA's Do Not Issue list. An AME cannot issue while you are taking it.

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Pilot Tip

Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.

Certification Details

FAA Status
Unacceptable (FAA Weight Loss Medication guidance); sympathomimetics are Do Not Issue
Certificate Classes
All classes — the AME must defer
Acceptable Alternatives
Orlistat, or a single diabetic medication such as metformin, liraglutide, Wegovy, or Zepbound when FAA criteria are met

Sources

  • FAA AME Guide — Pharmaceuticals: Weight Loss (faa.gov/ame_guide/media/Weight_loss_pharm.pdf)
  • FAA Do-Not-Issue/Do-Not-Fly Table (faa.gov/ame_guide/media/DNI_DNF_tables.pdf)

Last verified: 2026-09-12

Frequently Asked Questions

Is Phentermine-Topiramate allowed for pilots?

The FAA considers Phentermine-Topiramate (Qsymia) to be "Disqualifying" for medical certification purposes. The FAA lists phentermine-topiramate (Qsymia) as an unacceptable weight loss medication, prohibited as a single agent or in any combination product. Sympathomimetic weight loss drugs such as phentermine are also on the FAA's Do Not Issue list. An AME cannot issue while you are taking it.

What is the FAA status of Phentermine-Topiramate?

Phentermine-Topiramate has a status of "Disqualifying" under FAA medical certification policy. The certification pathway is: Unacceptable — prohibited weight loss medication.

Can I fly while taking Phentermine-Topiramate?

Phentermine-Topiramate is currently disqualifying for FAA medical certification. You cannot fly while taking this medication. A washout period and evaluation are typically required after discontinuation. Consult an AME or aviation attorney before making any medication changes.

Important Notice

The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.

The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.