Direct Oral Anticoagulant (DOAC)Conditionally Approved

Rivaroxaban

Brand names: Xarelto|Last verified: 2026-03-01

FAA Pathway: Special Issuance required — underlying condition evaluated

Rivaroxaban may be approved through Special Issuance depending on the underlying indication. Like apixaban, the DOAC itself is not specifically prohibited, but the condition requiring anticoagulation must be certifiable.

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Pilot Tip

Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.

Certification Details

Key Requirements
Stable dosing, underlying condition certifiable
Certificate Classes
Depends on underlying condition
Monitoring
Per treating physician and FAA requirements
Notes
Discuss with AME experienced in anticoagulation cases

Sources

  • FAA AME Guide — Pharmaceuticals: Anticoagulants (faa.gov/ame_guide/pharm/anticoag)

Last verified: 2026-03-01

Frequently Asked Questions

Is Rivaroxaban allowed for pilots?

The FAA considers Rivaroxaban (Xarelto) to be "Conditionally Approved" for medical certification purposes. Rivaroxaban may be approved through Special Issuance depending on the underlying indication. Like apixaban, the DOAC itself is not specifically prohibited, but the condition requiring anticoagulation must be certifiable.

What is the FAA status of Rivaroxaban?

Rivaroxaban has a status of "Conditionally Approved" under FAA medical certification policy. The certification pathway is: Special Issuance required — underlying condition evaluated.

Can I fly while taking Rivaroxaban?

Flying while taking Rivaroxaban may be possible through the FAA's Special Issuance process. You will need to meet specific requirements and obtain approval before exercising pilot privileges. Consult an experienced AME for guidance.

Important Notice

The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.

The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.